ATP11B

ATPase, class VI, type 11B
Identifiers
Symbols ATP11B ; ATPIF; ATPIR
External IDs OMIM: 605869 MGI: 1923545 HomoloGene: 32919 GeneCards: ATP11B Gene
EC number 3.6.3.1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 23200 76295
Ensembl ENSG00000058063 ENSMUSG00000037400
UniProt Q9Y2G3 Q6DFW5
RefSeq (mRNA) NM_014616 NM_029570
RefSeq (protein) NP_055431 NP_083846
Location (UCSC) Chr 3:
182.79 – 182.92 Mb		 Chr 3:
35.75 – 35.86 Mb
PubMed search

Probable phospholipid-transporting ATPase IF is an enzyme that in humans is encoded by the ATP11B gene.[1][2][3]

Function

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[3]

References

  1. ↑ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  2. ↑ Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA (Nov 1999). "Differential expression of putative transbilayer amphipath transporters". Physiological Genomics 1 (3): 139–50. PMID 11015572.
  3. 1 2 "Entrez Gene: ATP11B ATPase, Class VI, type 11B".

Further reading


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