AP3S2
| Adaptor-related protein complex 3, sigma 2 subunit | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | AP3S2 ; AP3S3; sigma3b | ||||||||||||
| External IDs | OMIM: 602416 MGI: 1337060 HomoloGene: 100592 GeneCards: AP3S2 Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10239 | 11778 | |||||||||||
| Ensembl | ENSG00000157823 | ENSMUSG00000063801 | |||||||||||
| UniProt | P59780 | Q8BSZ2 | |||||||||||
| RefSeq (mRNA) | NM_005829 | NM_009682 | |||||||||||
| RefSeq (protein) | NP_005820 | NP_033812 | |||||||||||
| Location (UCSC) |
Chr 15: 89.83 – 89.89 Mb |
Chr 7: 79.88 – 79.92 Mb | |||||||||||
| PubMed search | |||||||||||||
AP-3 complex subunit sigma-2 is a protein that in humans is encoded by the AP3S2 gene.[1][2]
Interactions
AP3S2 has been shown to interact with AP3B1.[3]
References
- ↑ Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS (Apr 1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
- ↑ "Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit".
- ↑ Dell'Angelica, E C; Ooi C E; Bonifacino J S (Jun 1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. (UNITED STATES) 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. ISSN 0021-9258. PMID 9182526.
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Dell'Angelica EC, Ooi CE, Bonifacino JS (1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. PMID 9182526.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Rous BA, Reaves BJ, Ihrke G; et al. (2002). "Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes". Mol. Biol. Cell 13 (3): 1071–82. doi:10.1091/mbc.01-08-0409. PMC 99620. PMID 11907283.
- Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC (2002). "BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules". J. Biol. Chem. 277 (31): 28191–9. doi:10.1074/jbc.M204011200. PMID 12019270.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Nie Z, Boehm M, Boja ES; et al. (2003). "Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1". Dev. Cell 5 (3): 513–21. doi:10.1016/S1534-5807(03)00234-X. PMID 12967569.
- Salazar G, Love R, Werner E; et al. (2004). "The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation". Mol. Biol. Cell 15 (2): 575–87. doi:10.1091/mbc.E03-06-0401. PMC 329249. PMID 14657250.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Lefrançois S, Janvier K, Boehm M; et al. (2004). "An ear-core interaction regulates the recruitment of the AP-3 complex to membranes". Dev. Cell 7 (4): 619–25. doi:10.1016/j.devcel.2004.08.009. PMID 15469849.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
External links
- AP3S2 human gene location in the UCSC Genome Browser.
- AP3S2 human gene details in the UCSC Genome Browser.
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