ALX4
Homeobox protein aristaless-like 4 is a protein that in humans is encoded by the ALX4 gene.[1][2][3]
Interactions
ALX4 has been shown to interact with Lymphoid enhancer-binding factor 1.[4]
References
- ↑ Wu YQ, Badano JL, McCaskill C, Vogel H, Potocki L, Shaffer LG (Nov 2000). "Haploinsufficiency of ALX4 as a potential cause of parietal foramina in the 11p11.2 contiguous gene-deletion syndrome". Am J Hum Genet 67 (5): 1327–32. doi:10.1016/S0002-9297(07)62963-2. PMC 1288575. PMID 11017806.
- ↑ Bartsch O, Wuyts W, Van Hul W, Hecht JT, Meinecke P, Hogue D, Werner W, Zabel B, Hinkel GK, Powell CM, Shaffer LG, Willems PJ (Jul 1996). "Delineation of a contiguous gene syndrome with multiple exostoses, enlarged parietal foramina, craniofacial dysostosis, and mental retardation, caused by deletions in the short arm of chromosome 11". Am J Hum Genet 58 (4): 734–42. PMC 1914683. PMID 8644736.
- ↑ "Entrez Gene: ALX4 aristaless-like homeobox 4".
- ↑ Boras, Kata; Hamel Paul A (Jan 2002). "Alx4 binding to LEF-1 regulates N-CAM promoter activity". J. Biol. Chem. (United States) 277 (2): 1120–7. doi:10.1074/jbc.M109912200. ISSN 0021-9258. PMID 11696550.
Further reading
- Qu S, Tucker SC, Zhao Q; et al. (1999). "Physical and genetic interactions between Alx4 and Cart1.". Development 126 (2): 359–69. PMID 9847249.
- Wuyts W, Cleiren E, Homfray T; et al. (2001). "The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500).". J. Med. Genet. 37 (12): 916–20. doi:10.1136/jmg.37.12.916. PMC 1734509. PMID 11106354.
- Mavrogiannis LA, Antonopoulou I, Baxová A; et al. (2001). "Haploinsufficiency of the human homeobox gene ALX4 causes skull ossification defects.". Nat. Genet. 27 (1): 17–8. doi:10.1038/83703. PMID 11137991.
- Nagase T, Nakayama M, Nakajima D; et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
- Boras K, Hamel PA (2002). "Alx4 binding to LEF-1 regulates N-CAM promoter activity.". J. Biol. Chem. 277 (2): 1120–7. doi:10.1074/jbc.M109912200. PMID 11696550.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Wakui K, Gregato G, Ballif BC; et al. (2005). "Construction of a natural panel of 11p11.2 deletions and further delineation of the critical region involved in Potocki-Shaffer syndrome.". Eur. J. Hum. Genet. 13 (5): 528–40. doi:10.1038/sj.ejhg.5201366. PMID 15852040.
- Mavrogiannis LA, Taylor IB, Davies SJ; et al. (2006). "Enlarged parietal foramina caused by mutations in the homeobox genes ALX4 and MSX2: from genotype to phenotype.". Eur. J. Hum. Genet. 14 (2): 151–8. doi:10.1038/sj.ejhg.5201526. PMC 1477589. PMID 16319823.
External links
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