ACER3
| Alkaline ceramidase 3 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ACER3 ; APHC; PHCA | ||||||||||||
| External IDs | MGI: 1913440 HomoloGene: 5410 IUPHAR: 2470 GeneCards: ACER3 Gene | ||||||||||||
| EC number | 3.5.1.23 | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 55331 | 66190 | |||||||||||
| Ensembl | ENSG00000078124 | ENSMUSG00000030760 | |||||||||||
| UniProt | Q9NUN7 | Q9D099 | |||||||||||
| RefSeq (mRNA) | NM_001300953 | NM_025408 | |||||||||||
| RefSeq (protein) | NP_001287882 | NP_079684 | |||||||||||
| Location (UCSC) |
Chr 11: 76.86 – 77.03 Mb |
Chr 7: 98.21 – 98.32 Mb | |||||||||||
| PubMed search | |||||||||||||
Alkaline ceramidase 3 also known as ACER3 is a ceramidase enzyme which in humans is encoded by the ACER3 gene.[1][2]
References
- ↑ Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM (July 2001). "Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide". J. Biol. Chem. 276 (28): 26577–88. doi:10.1074/jbc.M102818200. PMID 11356846.
- ↑ Mao C, Obeid LM (September 2008). "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate". Biochim. Biophys. Acta 1781 (9): 424–34. doi:10.1016/j.bbalip.2008.06.002. PMC 2614331. PMID 18619555.
Further reading
- Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Wheeler HE, Metter EJ, Tanaka T; et al. (2009). Gibson, Greg, ed. "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.". PLoS Genet. 5 (10): e1000685. doi:10.1371/journal.pgen.1000685. PMC 2752811. PMID 19834535.
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