4-Hydroxymandelic acid
Names | |
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IUPAC name
2-(4-Hydroxyphenyl)acetic acid | |
Other names
4-Hydroxyphenylglycolic acid; 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid; p-Hydroxymandelic acid, 4-Hydroxymandelate | |
Identifiers | |
1198-84-1 184901-84-6 (hydrate) | |
2365374 | |
ChemSpider | 321 |
EC Number | 214-839-7 |
Jmol interactive 3D | Image |
PubChem | 328 |
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Properties | |
C8H8O4 | |
Molar mass | 168.15 g·mol−1 |
Appearance | Light red powder |
Melting point | 89 °C (192 °F; 362 K) |
Hazards | |
Safety data sheet | MSDS at Sigma Aldrich |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
4-Hydroxymandelic acid is a chemical compound used to synthesize atenolol.[1] The compound typically occurs as a monohydrate (C8H8O4 • H2O at 186.16 g/mol).
Synthesis
4-Hydroxymandelic acid is obtained by the condensation reaction between phenol and glyoxylic acid.[1]
See also
References
- 1 2 Mattioda, Georges and Christidis, Yani (2000). "Glyoxylic Acid". Ullmann's Encyclopedia of Industrial Chemistry: pg. 2. doi:10.1002/14356007.a12_495. Retrieved 27 December 2013.
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