30S
Atomic structure of the 30S Subunit from Thermus thermophilus. Proteins are shown in blue and the single RNA strand in orange.[1]
30S is the smaller subunit of the 70S ribosome of prokaryotes. It is a complex of ribosomal RNA and ribonucleoproteins that functions in mRNA translation. It includes the 16S ribosomal RNA. It has about 21 basic proteins.
The 30S subunit is the site of inhibition for antibiotics such as tetracycline and aminoglycosides.
See also
50S is the larger subunit of the 70S ribosome of prokaryotes in the cell. It is the site of inhibition for antibiotics such as macrolides, chloramphenicol, clindamycin, and the pleuromutilins. It includes the 5S ribosomal RNA and 23S ribosomal RNA.
References
- ↑ Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A (2000). "Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution". Cell 102 (5): 615–23. doi:10.1016/S0092-8674(00)00084-2. PMID 11007480.
External links
- 16S rRNA, BioMineWiki
- http://pathmicro.med.sc.edu/mayer/antibiot.htm
- 16S Ribosomal RNA at the US National Library of Medicine Medical Subject Headings (MeSH)
| ||||||||||||||||
This article is issued from Wikipedia - version of the Saturday, September 19, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.