3-Oxopentanoic acid
Names | |
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IUPAC name
3-Oxopentanoic acid | |
Other names
beta-Ketopentanoate 3-Oxopentanoate 3-Oxovaleric acid 3-Ketovaleric acid | |
Identifiers | |
10191-25-0 | |
ChEBI | CHEBI:27401 |
ChemSpider | 388751 |
Jmol interactive 3D | Image Image |
KEGG | C02233 |
PubChem | 439684 |
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Properties | |
C5H8O3 | |
Molar mass | 116.12 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
3-Oxopentanoic acid, or beta-ketopentanoate, is a 5-carbon ketone body. It is made from odd carbon fatty acids in the liver and rapidly enters the brain.
As opposed to 4-carbon ketone bodies, beta-ketopentanoate is anaplerotic, meaning it can refill the pool of TCA cycle intermediates. The triglyceride triheptanoin is used clinically to produce beta-ketopentanoate.[1]
References
- ↑ Renée P. Kinman, Takhar Kasumov, Kathryn A. Jobbins, Katherine R. Thomas, Jillian Adams, Lisa N. Brunengraber, Gerd Kutz, Wolf-Ulrich Brewer, Charles R. Roe, and Henri Brunengraber (2006). "Parenteral and Enteral Metabolism of Anaplerotic Triheptanoin in Normal Rats". Am J Physiol Endocrinol Metab 291 (4): E860–E866. doi:10.1152/ajpendo.00366.2005. PMID 16705058. Reprint
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