Zofenopril
 | |
| Systematic (IUPAC) name | |
|---|---|
| (2S,4S)-1-((S)-3-(benzoylthio)-2-methylpropanoyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Oral | |
| Identifiers | |
81872-10-8  | |
| C09AA15 | |
| PubChem | CID 92400 |
| ChemSpider |
83422  |
| UNII |
290ZY759PI |
| KEGG |
D08688 |
| ChEBI |
CHEBI:78539 |
| ChEMBL |
CHEMBL331378 |
| Chemical data | |
| Formula | C22H23NO4S2 |
| 429.552 g/mol | |
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SMILES
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Zofenopril (also known as zofenoprilum [Latin]) is an angiotensin converting enzyme (ACE) inhibitor with cardioprotective properties indicated for the treatment of hypertension.[1]
In small studies, zofenopril appeared significantly more effective than the older antihypertensives atenolol and enalapril, and was associated with fewer adverse effects.[2][3]
References
- ↑ Ambrosioni E (2007). "Defining the role of zofenopril in the management of hypertension and ischemic heart disorders". Am J Cardiovasc Drugs 7 (1): 17–24. doi:10.2165/00129784-200707010-00002. PMID 17355163.
- ↑ Nilsson P (October 2007). "Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension". Blood Press Suppl 2: 25–30. PMID 18046976.
- ↑ Mallion JM (October 2007). "An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension". Blood Press Suppl 2: 13–8. PMID 18046974.
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