Zerumbone synthase

Zerumbone synthase
Identifiers
EC number 1.1.1.326
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Zerumbone synthase (EC 1.1.1.326, ZSD1) is an enzyme with system name 10-hydroxy-alpha-humulene:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

10-hydroxy-alpha-humulene + NAD+ \rightleftharpoons zerumbone + NADH + H+

The enzyme was cloned from shampoo ginger, Zingiber zerumbet.

References

  1. Okamoto, S., Yu, F., Harada, H., Okajima, T., Hattan, J., Misawa, N. and Utsumi, R. (2011). "A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet". FEBS J. 278 (16): 2892–2900. doi:10.1111/j.1742-4658.2011.08211.x. PMID 21668645.

External links