ZDHHC17

Zinc finger, DHHC-type containing 17
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsZDHHC17 ; HIP14; HIP3; HYPH
External IDsOMIM: 607799 MGI: 2445110 HomoloGene: 56324 GeneCards: ZDHHC17 Gene
EC number2.3.1.225
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez23390320150
EnsemblENSG00000186908ENSMUSG00000035798
UniProtQ8IUH5Q80TN5
RefSeq (mRNA)NM_015336NM_172554
RefSeq (protein)NP_056151NP_766142
Location (UCSC)Chr 12:
77.16 – 77.25 Mb
Chr 10:
110.94 – 111.01 Mb
PubMed search

Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene.[1][2][3]

Interactions

ZDHHC17 has been shown to interact with Huntingtin.[4][5]

References

  1. Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Oct 1998). "Huntingtin interacts with a family of WW domain proteins". Hum Mol Genet 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.
  2. Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport". J Biol Chem 283 (48): 33365–74. doi:10.1074/jbc.M801469200. PMC 2662264. PMID 18794299.
  3. "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17".
  4. Faber, P W; Barnes G T; Srinidhi J; Chen J; Gusella J F; MacDonald M E (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Hum. Mol. Genet. (ENGLAND) 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. ISSN 0964-6906. PMID 9700202.
  5. Singaraja, Roshni R; Hadano Shinji, Metzler Martina, Givan Scott, Wellington Cheryl L, Warby Simon, Yanai Anat, Gutekunst Claire-Anne, Leavitt Blair R, Yi Hong, Fichter Keith, Gan Lu, McCutcheon Krista, Chopra Vikramjit, Michel Jennifer, Hersch Steven M, Ikeda Joh-E, Hayden Michael R (Nov 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis". Hum. Mol. Genet. (England) 11 (23): 2815–28. doi:10.1093/hmg/11.23.2815. ISSN 0964-6906. PMID 12393793.

Further reading