YybP-ykoY leader
| yybP-ykoY leader | |
|---|---|
 | |
| Predicted secondary structure and sequence conservation of yybP-ykoY | |
| Identifiers | |
| Symbol | yybP-ykoY |
| Alt. Symbols | SraF |
| Rfam | RF00080 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Bacteria |
| SO | 0000233 |
The yybP-ykoY leader RNA element was originally discovered in E. coli during a large scale screen and was named SraF.[1] This family was later found to exist upstream of related families of protein genes in many bacteria, including the yybP and ykoY genes in B. subtilis. The specific functions of these proteins are unknown, but this structured RNA element may be involved in their genetic regulation as a riboswitch.[2]
References
- ↑ Argaman, L; Hershberg R; Vogel J; Bejerano G; Wagner EG; Margalit H; Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr Biol 11 (12): 941–950. doi:10.1016/S0960-9822(01)00270-6. PMID 11448770.
- ↑ Barrick, JE; Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR (2004). "New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control". Proc Natl Acad Sci USA 101 (17): 6421–6426. doi:10.1073/pnas.0308014101. PMC 404060. PMID 15096624.