Xi River virus

Xi River virus
Virus classification
Group: Group III (dsRNA)
Order: Unassigned
Family: Reoviridae
Subfamily: Spinareovirinae
Genus: Orthoreovirus
Type species
Pteropine orthoreovirus
Species

Xi River virus

Xi River virus, (XRV), is a putative novel bat species in the genus Orthoreovirus isolated from fruit bats in Guangdong Province in southern China. It is the first bat reovirus isolated in China.[1][2]

Virology

Genome


Only a partial sequence of XRV was isolated from the fruit bat, but based on its open reading frame it was identified as a reovirus.[1] XRV has the same morphology and high sequence identity as Nelson Bay virus (NBV), and a 10-segmented double-stranded RNA genome, as well as high sequence identity to NBV members.[3][4]

Reoviruses are non-enveloped, double-stranded RNA viruses. They have an icosahedral capsid (T-13) composed of an outer and inner protein shell. The genome contains 10–12 segments grouped into three categories by size: L (large), M (medium) and S (small). Segments range from ~ 3.9 kbp – 1kbp and each segment encodes 1–3 proteins. Reoviridae proteins are denoted by the Greek character corresponding to the segment it was translated from (the L segment encodes for λ proteins, the M segment encodes for μ proteins and the S segment encodes for σ proteins).[3][4]

See also

References

  1. ↑ 1.0 1.1 Du L, Lu Z, Fan Y, Meng K, Jiang Y, Zhu Y, Wang S, Gu W, Zou X, Tu C. Xi River virus, a new bat reovirus isolated in southern China.Arch Virol. 2010 Aug;155(8):1295–9. doi: 10.1007/s00705-010-0690-4. Epub 2010 May 22.
  2. ↑ http://online.liebertpub.com/doi/abs/10.1089/vbz.2008.0212
  3. ↑ 3.0 3.1 Patton JT (editor). (2008). Segmented Double-stranded RNA Viruses: Structure and Molecular Biology. Caister Academic Press. ISBN 978-1-904455-21-9. http://www.horizonpress.com/rnav.
  4. ↑ 4.0 4.1 MicrobiologyBytes – Reoviruses

External links