Xanthosine triphosphate

Xanthosine triphosphate
Names

IUPAC name [(2R,3S,4R)-5-(2,6-dioxo-3H-purin-9-yl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Identifiers
CAS Registry Number	6253-56-1^N
ChemSpider	19980202^Y
InChI InChI=1S/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;31-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1^Y Key: BKBQKVXTMZOVRH-CYCLDIHTSA-N^Y InChI=1/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;31-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1 Key: BKBQKVXTMZOVRH-CYCLDIHTBT
Jmol-3D images	Image
PubChem	121887
SMILES OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.O=C3Nc2c(ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)N3
Properties
Chemical formula	C₁₀H₁₅N₄O₁₅P₃
Molar mass	524.17 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
N verify (what is: Y/N?)
Infobox references

Xanthosine 5'-triphosphate (XTP) is a nucleotide that is not produced by - and has no known function in - living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. Deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP.^[1]

References

↑ Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.

Xanthosine triphosphate

References

See also