William Guthrie (disambiguation)

William Guthrie (born 1967) is an American pugilist.

William Guthrie may also refer to:

• William Guthrie (historian) (1708–1770), Scottish writer and journalist
• William Guthrie (politician) (1884–?), Canadian politician
• William Guthrie (Puritan) (1620-1665), Scottish Presbyterian minister and author
• William Dameron Guthrie (1859–1935), American lawyer
• William Norman Guthrie (1868–1944), American clergyman