Viqualine

Viqualine
Systematic (IUPAC) name
4-[3-[(3R,4R)-3-ethenylpiperidin-4-yl]propyl]-6-methoxyquinoline
Clinical data
Identifiers
72714-74-0
PubChem CID 3050111
ChemSpider 2312222
UNII 1Y3A5E2L1J Yes
ChEMBL CHEMBL2104497
Chemical data
Formula C20H26N2O
310.432 g/mol
 Yes (what is this?)  (verify)

Viqualine (PK-5078) is a psychoactive drug and research chemical of the quinoline chemical class that possesses antidepressant and anxiolytic properties.[1] It acts as a selective serotonin releasing agent (SSRA).[2] It has mainly been researched as a potential treatment for alcoholism.[3][4]

References

  1. ↑ Faravelli C, Albanesi G, Sessarego A (1988). "Viqualine in resistant depression: a double-blind, placebo-controlled trial". Neuropsychobiology 20 (2): 78–81. doi:10.1159/000118477. PMID 3075725.
  2. ↑ Le Fur G, Imbault F, Mitrani N, Marquis F, Renault C, Dubroeucq MC, Gueremy C, Uzan A (February 1984). "The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives". Neuropharmacology 23 (2A): 169–73. doi:10.1016/S0028-3908(84)80010-6. PMID 6717757.
  3. ↑ Naranjo CA, Sellers EM (1989). "Serotonin uptake inhibitors attenuate ethanol intake in problem drinkers". Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 7: 255–66. PMID 2522667.
  4. ↑ Naranjo CA, Sullivan JT, Kadlec KE, Woodley-Remus DV, Kennedy G, Sellers EM (September 1989). "Differential effects of viqualine on alcohol intake and other consummatory behaviors". Clinical Pharmacology and Therapeutics 46 (3): 301–9. doi:10.1038/clpt.1989.142. PMID 2673621.