Vapreotide

Systematic (IUPAC) name

2-Amino-N-[10-(4-aminobutyl)-4-{[1-carbamoyl-2-(1H-indol-2-yl)ethyl]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide
Clinical data
Trade names	Sanvar
Pharmacokinetic data
Half-life	30 minutes
Identifiers
CAS Registry Number	103222-11-3
ATC code	H01CB04
PubChem	CID 23725064
DrugBank	DB04894
ChemSpider	64425
UNII	2PK59M9GFF
KEGG	D06281
Synonyms	Octastatin
Chemical data
Formula	C₅₇H₇₀N₁₂O₉S₂
Molecular mass	1131.37 g/mol
SMILES C(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=C2C=CC=C3)NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CSSCC(NC1=O)C(=O)NC(CC1=CC2=C(N1)C=CC=C2)C(N)=O)NC(=O)C(N)CC1=CC=CC=C1
Physical data
Density	1.4 g/cm³
Boiling point	1,540.9 °C (2,805.6 °F)

Vapreotide (Sanvar) is a synthetic somatostatin analog. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea.^[1]

References

Hypothalamic

GNRH	Agonists: Gonadorelin Nafarelin Histrelin Antagonists: Cetrorelix Ganirelix

Somatostatin	Agonists: Lanreotide Octreotide Pasireotide Vapreotide

ACTH	Agonists: Corticotropin Cosyntropin Tetracosactide

GH	Agonists: IGF-1 (Mecasermin/Mecasermin rinfabate) Sermorelin Somatrem Tesamorelin Antagonists: Pegvisomant

TSH	Agonists: Thyrotropin

Oxytocin	Agonists: Argiprestocin Aspartocin Carbetocin Cargutocin Demoxytocin Nacartocin Antagonists: Atosiban Barusiban

Vasopressin	Agonists: Argipressin Desmopressin Felypressin Lypressin Ornipressin Terlipressin Antagonists: Conivaptan Demeclocycline Lixivaptan Mozavaptan Nelivaptan Relcovaptan Satavaptan Tolvaptan

Index of hormones

Description	Glands Hormones thyroid intermediates metabolism mineralocorticoids Physiology Development

Disease	Diabetes Congenital Neoplasms and cancer Other Symptoms and signs eponymous

Treatment	Procedures Drugs calcium balance corticosteroids oral hypoglycemics pituitary and hypothalamic thyroid