Usutu virus

Usutu virus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Usutu virus

Usutu virus (USUV) first identified in South Africa in 1959,[1] is an emerging zoonotic arbovirus of concern because of its pathogenicity to humans and its similarity in ecology with other emerging arboviruses such as West Nile Virus.[2] USUV is a flavivirus belonging to the Japanese encephalitis complex.[2]

USUV has been reported from several African countries including Senegal, Central African Republic, Nigeria, Uganda, Burkina Faso, Cote d'Ivoire, and Morocco.[2] Only two human cases have been identified in Africa, in 1981 and 2004, with one benign and one severe case described.[2] The virus was identified for the first time outside of Africa in 2001 in Austria, where it caused significant mortality among Old World blackbirds in Vienna.[3] The first human case outside of Africa was reported in Italy in 2009, where an immunocompromised patient was infected, causing encephalitis.[4]

USUV's host range includes primarily Culex mosquitoes, birds, and humans.[2]

References

  1. McIntosh, Bruce M. (1985). "Usutu (SA Ar 1776), nouvel arbovirus du groupe B.". International Catalogue of Arboviruses 3: 1059–1060.
  2. 2.0 2.1 2.2 2.3 2.4 Nikolay, Birgit; Diallo, Mawlouth; Boye, Cheikh Saad Bouh; Sall, Amadou Alpha (November 2011). "Usutu Virus in Africa". Vector-Borne and Zoonotic Diseases 11 (11): 1417–1423. doi:10.1089/vbz.2011.0631. PMID 21767160.
  3. Weissenböck, H.; Kolodziejek, J.; Url, A.; Lussy, H.; Rebel-Bauder, B.; Nowotny, N. (July 2002). "Emergence of Usutu virus, an African Mosquito-Borne Flavivirus of the Japanese Encephalitis Virus Group, Central Europe". Emerging Infectious Diseases 8 (7): 652–656. doi:10.3201/eid0807.020094. PMC 2730324. PMID 12095429.
  4. Pecorari, M.; Longo, G.; Gennari, W.; Grottola, A.; Sabbatini, A.; Tagliazucchi, S.; Savini, G.; Monaco, F.; Simone, M. (17 December 2009). "First human case of Usutu virus neuroinvasive infection, Italy, August-September 2009". Eurosurveillance 14 (50). PMID 20070936.