Urtoxazumab

Urtoxazumab^?

Monoclonal antibody
Type	Whole antibody
Source	Humanized (from mouse)
Target	E. coli Shiga-like toxin II B subunit
Clinical data
Identifiers
CAS Registry Number	502496-16-4 N
ATC code	None
Chemical data
Formula	C6414H9934N1718O2010S40
Molecular mass	144.6 kDa
N (what is this?)  (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.^[1][2]

References

1. ↑ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
2. ↑ López, EL; Contrini, MM; Glatstein, E; González Ayala, S; Santoro, R; Allende, D; Ezcurra, G; Teplitz, E et al. (2009). "Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody Against Shiga-Like Toxin 2 in Healthy Adults and Pediatric STEC- Infected Patients". Antimicrobial agents and chemotherapy 54 (1): 239–243. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.