UNC84B

Sad1 and UNC84 domain containing 2

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
3UNP, 4DXR, 4DXS, 4DXT, 4FI9

Identifiers

Symbols

SUN2 ; UNC84B

External IDs

OMIM: 613569 MGI: 2443011 HomoloGene: 9113 GeneCards: SUN2 Gene

Gene ontology
Molecular function	• protein binding • lamin binding • microtubule binding • identical protein binding
Cellular component	• nuclear chromosome, telomeric region • condensed nuclear chromosome • nuclear envelope • nuclear inner membrane • endosome membrane • integral component of membrane • nuclear membrane • SUN-KASH complex
Biological process	• nuclear envelope organization • mitotic spindle organization • nuclear migration • positive regulation of cell migration • nuclear migration along microfilament • centrosome localization • cytoskeletal anchoring at nuclear membrane • nuclear matrix anchoring at nuclear membrane
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 22:
39.13 – 39.19 Mb

Chr 15:
79.72 – 79.74 Mb

PubMed search

Protein unc-84 homolog B is a protein that in humans is encoded by the UNC84B gene.^[1]^[2]^[3]

References

↑ Raff JW (Feb 2000). "The missing (L) UNC?". Curr Biol 9 (18): R708–10. doi:10.1016/S0960-9822(99)80446-1. PMID 10508607.
↑ Malone CJ, Fixsen WD, Horvitz HR, Han M (Aug 1999). "UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development". Development 126 (14): 3171–81. PMID 10375507.
↑ "Entrez Gene: UNC84B unc-84 homolog B (C. elegans)".

Andersson B, Wentland MA, Ricafrente JY et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Ishikawa K, Nagase T, Suyama M et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
Dunham I, Shimizu N, Roe BA et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
Hoffenberg S, Liu X, Nikolova L et al. (2000). "A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion.". J. Biol. Chem. 275 (32): 24661–9. doi:10.1074/jbc.M909600199. PMID 10818110.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Grønborg M, Kristiansen TZ, Stensballe A et al. (2003). "A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate.". Mol. Cell Proteomics 1 (7): 517–27. doi:10.1074/mcp.M200010-MCP200. PMID 12239280.
Sun G, Yuen Chan S, Yuan Y et al. (2002). "Isolation of differentially expressed genes in human heart tissues.". Biochim. Biophys. Acta 1588 (3): 241–6. doi:10.1016/S0925-4439(02)00171-0. PMID 12393179.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Schirmer EC, Florens L, Guan T et al. (2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics.". Science 301 (5638): 1380–2. doi:10.1126/science.1088176. PMID 12958361.
Ibarrola N, Kalume DE, Gronborg M et al. (2004). "A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture.". Anal. Chem. 75 (22): 6043–9. doi:10.1021/ac034931f. PMID 14615979.
Collins JE, Wright CL, Edwards CA et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Crisp M, Liu Q, Roux K et al. (2006). "Coupling of the nucleus and cytoplasm: role of the LINC complex.". J. Cell Biol. 172 (1): 41–53. doi:10.1083/jcb.200509124. PMC 2063530. PMID 16380439.
Mehrle A, Rosenfelder H, Schupp I et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

UNC84B

References

Further reading