ULK1
Serine/threonine-protein kinase ULK1 is an enzyme that in humans is encoded by the ULK1 gene.[1][2]
Interactions
ULK1 has been shown to interact with GABARAPL2,[3] GABARAP,[3][4] SYNGAP1[5] and SDCBP.[5]
References
- ↑ Kuroyanagi H, Yan J, Seki N, Yamanouchi Y, Suzuki Y, Takano T, Muramatsu M, Shirasawa T (September 1998). "Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment". Genomics 51 (1): 76–85. doi:10.1006/geno.1998.5340. PMID 9693035.
- ↑ "Entrez Gene: ULK1 unc-51-like kinase 1 (C. elegans)".
- ↑ 3.0 3.1 Okazaki, N; Yan J; Yuasa S; Ueno T; Kominami E; Masuho Y; Koga H; Muramatsu M (December 2000). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation". Brain Res. Mol. Brain Res. (Netherlands) 85 (1–2): 1–12. doi:10.1016/S0169-328X(00)00218-7. ISSN 0169-328X. PMID 11146101.
- ↑ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- ↑ 5.0 5.1 Tomoda, Toshifumi; Kim Jee Hae; Zhan Caixin; Hatten Mary E (March 2004). "Role of Unc51.1 and its binding partners in CNS axon outgrowth". Genes Dev. (United States) 18 (5): 541–58. doi:10.1101/gad.1151204. ISSN 0890-9369. PMC 374236. PMID 15014045.
Further reading
- Nagase T; Ishikawa K; Suyama M et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Okazaki N; Yan J; Yuasa S et al. (2001). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation". Brain Res. Mol. Brain Res. 85 (1–2): 1–12. doi:10.1016/S0169-328X(00)00218-7. PMID 11146101.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Tomoda T, Kim JH, Zhan C, Hatten ME (2004). "Role of Unc51.1 and its binding partners in CNS axon outgrowth". Genes Dev. 18 (5): 541–58. doi:10.1101/gad.1151204. PMC 374236. PMID 15014045.
- Young AR; Chan EY; Hu XW et al. (2006). "Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes". J. Cell. Sci. 119 (Pt 18): 3888–900. doi:10.1242/jcs.03172. PMID 16940348.
- Olsen JV; Blagoev B; Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Wissing J; Jänsch L; Nimtz M et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry". Mol. Cell Proteomics 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.
- Ewing RM; Chu P; Elisma F et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Chan EY, Kir S, Tooze SA (2007). "siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy". J. Biol. Chem. 282 (35): 25464–74. doi:10.1074/jbc.M703663200. PMID 17595159.