Triflubazam

Triflubazam

Systematic (IUPAC) name
1-methyl- 5-phenyl- 7-(trifluoromethyl)- 1H-1,5-benzodiazepine- 2,4(3H,5H)-dione
Clinical data
Identifiers
CAS Registry Number	22365-40-8 Y
ATC code	None
PubChem	CID 31157
ChemSpider	28907 Y
UNII	80D8H0388T Y
Chemical data
Formula	C17H13F3N2O2
Molecular mass	334.29
SMILES FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
InChI InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3  Y Key:DMNPCIKBNDKNTO-UHFFFAOYSA-N  Y
Y (what is this?)  (verify)

Triflubazam^[1] is a drug which is a 1,5-benzodiazepine derivative, related to clobazam.^[2] It has sedative and anxiolytic effects, with a long half-life and duration of action.^[3][4][5]

See also

• Benzodiazepine
• Clobazam
• CP-1414S

References

1. ↑ US Patent 3660381 -5-ARYL-1H-1 5-BENZODIAZEPINE-2 4-DIONES
2. ↑ Lundbeck Institute (2003). "triflubazam". psychotropics.dk. Retrieved 17 November 2010. 
3. ↑ Itil TM, Akpinar S, Fink M: Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Current Therapeutic Research 1976; 19: 307-315
4. ↑ Csanalosi I, Pereira-Oran J, Case G, et al.: Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis. Current Therapeutic Research 1977; 22: 166-171
5. ↑ Nicholson AN, Stone BM, Clarke CH. Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. British Journal of Clinical Pharmacology. 1977 Oct;4(5):567-72.