Tosufloxacin
Tosufloxacin|
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| Systematic (IUPAC) name |
|---|
|
7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Clinical data |
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| AHFS/Drugs.com |
International Drug Names |
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| Identifiers |
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100490-36-6  Y |
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None |
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| PubChem |
CID 5517 |
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| ChemSpider |
5316  N |
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| UNII |
GHJ553KQPS N |
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| KEGG |
D02317 Y |
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| ChEBI |
CHEBI:77573 N |
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| ChEMBL |
CHEMBL273348 N |
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| Chemical data |
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| Formula |
C19H15F3N4O3 |
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|
404.34 g/mol |
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SMILES
- NC1CCN(C1)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F
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InChI=1S/C19H15F3N4O3/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29)
N
Key:WUWFMDMBOJLQIV-UHFFFAOYSA-N
N
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| N (what is this?) (verify) |
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Tosufloxacin is a fluoroquinolone antibiotic. It has a controversial safety profile in relation to other fluoroquinolones. It is associated with severe thrombocytopenia and nephritis, and hepatotoxicity.[1] It is sold in Japan under the brand name Ozex.
See also
References
- ↑ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy. 47 Suppl 3: 3–8; discussion 44–8. doi:10.1159/000057838. PMID 11549783.
