Tombusvirus

Tombusvirus
Virus classification
Group: Group IV ((+)ssRNA)
Order: Unassigned
Family: Tombusviridae
Genus: Tombusvirus
Type species
Tomato bushy stunt virus
Species

Lettuce necrotic stunt virus
Moroccan pepper virus
Tomato bushy stunt virus

The genus Tombusvirus are part of the family Tombusviridae and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA with a genome size of 4800 nucleotides. The virions are non-enveloped with a diameter of 30 nm and have an isometric nucleocapsid (icosahedral; T=3). These virions have a regular surface structure and are composed of 17% nucleic acid.

This genera of viruses include the tomato bushy stunt virus (hence the name).

The virus uses the cis-regulatory elements, Tombus virus defective interfering (DI) RNA region 3 and Tombusvirus 5' UTR to control expression of defective interfering RNAs and viral RNA replication.[1][2]

References

  1. ↑ Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–57. doi:10.1128/JVI.77.1.245-257.2003. PMC 140596. PMID 12477830.
  2. ↑ Wu B, Vanti WB, White KA (2001). "An RNA domain within the 5' untranslated region of the tomato bushy stunt virus genome modulates viral RNA replication". J. Mol. Biol. 305 (4): 741–56. doi:10.1006/jmbi.2000.4298. PMID 11162089.

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