Ticlatone

Ticlatone
Systematic (IUPAC) name

6-chloro-1,2-benzothiazol-3(2H)-one
Clinical data
Trade names	Landromil
Identifiers
CAS Registry Number	70-10-0^Y
ATC code	D01AE08
PubChem	CID 6258
ChemSpider	6022^N
UNII	BHW384Q9GI^Y
KEGG	D06139^Y
Chemical data
Formula	C₇H₄Cl N O S
Molecular mass	185.63 g/mol
SMILES c1cc2c(cc1Cl)s[nH]c2=O
InChI InChI=1S/C7H4ClNOS/c8-4-1-2-5-6(3-4)11-9-7(5)10/h1-3H,(H,9,10) ^N Key:POPOYOKQQAEISW-UHFFFAOYSA-N ^N
Physical data
Melting point	270 to 273 °C (518 to 523 °F)
N (what is this?) (verify)

Ticlatone (trade name Landromil) is an antifungal.^[1]

References

↑ Landromil (Ticlatone)

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	Topical: bifonazole butoconazole clomidazole clotrimazole^#, croconazole econazole fenticonazole ketoconazole isoconazole miconazole^#, neticonazole omoconazole oxiconazole sertaconazole sulconazole tioconazole

Triazoles	Topical: (fluconazole^#, fosfluconazole terconazole) Systemic: (fluconazole hexaconazole isavuconazole^†, itraconazole posaconazole voriconazole) Unknown: (albaconazole)

Thiazoles	Topical: (abafungin)

Polyene antimycotics
(ergosterol binding)

Topical: (hamycin
natamycin
nystatin^#)
Systemic: (amphotericin B^#, hamycin)

Allylamines
(squalene monooxygenase
inhibitors)

Topical: (amorolfine
butenafine
naftifine
terbinafine)
Systemic: terbinafine

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of fungal disease

Description	Fungi Classification

Disease	Fungus

Treatment	Drugs