Tiazofurin
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| Systematic (IUPAC) name | |
|---|---|
| (1R)-1-[4-(aminocarbonyl)-1,3-thiazol-2-yl]-1,4-anhydro-D-ribitol | |
| Clinical data | |
| Identifiers | |
| 60084-10-8 | |
| L01XX18 | |
| PubChem | CID 457954 |
| ChemSpider |
403014  |
| UNII |
ULJ82834RE |
| ChEMBL |
CHEMBL108358 |
| Synonyms | 2-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide |
| Chemical data | |
| Formula | C9H12N2O5S |
| 260.268 g/mol | |
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SMILES
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Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.[1]
References
- ↑ Popsavin M, Torović L, Svircev M et al. (2006). "Synthesis and antiproliferative activity of two new tiazofurin analogues with 2'-amido functionalities". Bioorg. Med. Chem. Lett. 16 (10): 2773–6. doi:10.1016/j.bmcl.2006.02.001. PMID 16495053.
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