Tetrindole

Tetrindole
Systematic (IUPAC) name


2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole
Clinical data
Identifiers
CAS Registry Number	^Y
ATC code	None
PubChem	CID 160020
ChemSpider	140675^Y
ChEBI	CHEBI:77799^N
Chemical data
Formula	C₂₀H₂₆N₂
Molecular mass	294.43 g/mol
SMILES c15c4n(c2ccc(cc12)C3CCCCC3)CCNC4CCC5
InChI InChI=1S/C20H26N2/c1-2-5-14(6-3-1)15-9-10-19-17(13-15)16-7-4-8-18-20(16)22(19)12-11-21-18/h9-10,13-14,18,21H,1-8,11-12H2 ^Y Key:AUXCHYJDVJZEPG-UHFFFAOYSA-N ^Y
N (what is this?) (verify)

Tetrindole is a drug candidate that functions by inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s.^[1] Tetrindole is similar in its chemical structure to pirazidol, pirlindole, and metralindole.^[2]

References

↑ Medvedev, Alexei E.; Alexandra A. Kirkel, Natalia S. Kamyshanskaya, Tatyana A. Moskvitina, Ludmila N. Axenova, Vladimir Z. Gorkin, Natalia I. Andreeva, Svetlana M. Golovina and Mikhail D. Mashkovsky (20 January 1994). "Monoamine oxidase inhibition by novel antidepressant tetrindole". Biochemical Pharmacology 47 (2): 303–308. doi:10.1016/0006-2952(94)90021-3. PMID 8304974.
↑ Ramsay RR, Gravestock MB. Monoamine oxidases: to inhibit or not to inhibit. Mini Rev Med Chem. 2003 Mar;3(2):129-36. PMID 12570845