Technetium (99mTc) medronic acid

Technetium (^99mTc) medronic acid
Systematic (IUPAC) name

Methylenebis(phosphonic acid) technetium (^99mTc)
Clinical data
Routes of administration	intravenous
Identifiers
ATC code	V09BA02
PubChem	CID 157443
Chemical data
Formula	CH₆O₆P₂ • x^99mTc
Molecular mass	unknown
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Technetium (^99mTc) medronic acid is a pharmaceutical product used in nuclear medicine to localize bone metastases^[1] as well as other diseases that can alter the natural turn-over in the bone.^[2]

Chemistry

The drug is a complex of medronic acid, the simplest bisphosphonate, with technetium-99m (^99mTc), a radionuclide that emits gamma rays. The exact structure of the complex is not known.^[2]^[3]

References

Diagnostic radiopharmaceuticals (V09)

Central nervous system	^99mTc (Exametazime) ¹²³I (Ioflupane Iofetamine Iomazenil) ¹⁸F (Florbetapir, Flutemetamol)

Skeletal system	^99mTc (Medronic acid)

Renal	¹²³I (Sodium iodohippurate) ⁶⁴Cu (Cu-ETS2)

Hepatic/reticuloendothelial	⁷⁵Se (SeHCAT)

Respiratory system	¹³³Xe ^81mKr

Cardiovascular system	^99mTc (Sestamibi Tetrofosmin) ¹¹¹In (Imciromab) ⁸²Rb (Rubidium chloride)

Inflammation/infection	^99mTc (Exametazime Sulesomab Tilmanocept) ¹¹¹In ⁶⁷Ga

Tumor	^99mTc (Arcitumomab Votumumab Hynic-octreotide) ¹¹¹In (Capromab pendetide Satumomab pendetide) ¹²⁵I (CC49) ¹²³I/¹³¹I (Iobenguane) ¹⁸F (Fludeoxyglucose Sodium fluoride)

Adrenal cortex	¹²³I/¹²⁵I (Iodocholesterol)

Radionuclides (including tracers)	positron (PET): ¹⁸F ¹¹C ⁶⁴Cu ¹³N ¹⁵O ⁶⁸Ga gamma ray/photon (SPECT/scintigraphy): ^99mTc ¹²³I ¹²⁵I ¹³¹I ¹¹¹In ⁵⁷Co ¹⁵³Sm ¹³³Xe ⁵¹Cr ^81mKr ²⁰¹Tl ⁶⁷Ga ⁷⁵Se