TUBE1
| Tubulin, epsilon 1 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | TUBE1 ; TUBE; dJ142L7.2 | ||||||||||||
| External IDs | OMIM: 607345 HomoloGene: 17762 GeneCards: TUBE1 Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 51175 | 71924 | |||||||||||
| Ensembl | ENSG00000074935 | ENSMUSG00000019845 | |||||||||||
| UniProt | Q9UJT0 | Q9D6T1 | |||||||||||
| RefSeq (mRNA) | NM_016262 | NM_028006 | |||||||||||
| RefSeq (protein) | NP_057346 | NP_082282 | |||||||||||
| Location (UCSC) | Chr 6: 112.39 – 112.41 Mb | Chr 10: 39.13 – 39.15 Mb | |||||||||||
| PubMed search | |||||||||||||
Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene. [1] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication
References
- ↑ "Entrez Gene: Tubulin, epsilon 1". Retrieved 2012-06-06.
Further reading
- Chang, P.; Giddings, T. H.; Winey, M.; Stearns, T. (2002). "Ɛ-Tubulin is required for centriole duplication and microtubule organization". Nature Cell Biology 5 (1): 71–76. doi:10.1038/ncb900. PMID 12510196.
- Zanic, M.; Stear, J. H.; Hyman, A. A.; Howard, J. (2009). May, Robin Charles, ed. "EB1 Recognizes the Nucleotide State of Tubulin in the Microtubule Lattice". PLoS ONE 4 (10): e7585. doi:10.1371/journal.pone.0007585. PMC 2761489. PMID 19851462.
- Stearns, T.; Chang, P. (1999). "Delta-tubulin and epsilon-tubulin: Two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology 2 (1): 30–35. doi:10.1038/71350. PMID 10620804.