TSD
TSD may refer to:
- Tang Soo Do (tangsudo), a martial art
- Target-to-skin distance, a measurement in external beam radiotherapy
- Tay–Sachs disease, a genetic disorder, fatal in its most common variant
- Technical Services Division, another term for the CIA's Technical Services Staff
- Technical specifications document
- Temperature-dependent sex determination
- Texas School for the Deaf
- Text, Speech and Dialogue, an international conference
- Thermionic specific detector, another term for nitrogen–phosphorus detector
- Time-speed-distance rally, another term for regularity rally in motorsport
- Total sleep deprivation
- Transylvanian Society of Dracula
- Treasury Solicitor's Department
- TSD (band), a 1990's girl band
- Turtle saving device, another term for turtle excluder device
- University of Wales Trinity Saint David, a university