TRPA1 receptor agonist

TRPA1 receptor agonists are substances that agonize transient receptor potential cation channel, member A1 receptors.[1][2]

Effects

Hypothesized molecular identity of cold-sensitive afferents based upon the expression of TRPM8 and TRPA1

TRPA1 agonists have been and remain the subject of research into their potential thermoreceptoric activity.[1][2]

Examples

References

  1. ↑ 1.0 1.1 McKemy, David D. (2005-04-22). "How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation". Molecular Pain 1 (16). doi:10.1186/1744-8069-1-16. Retrieved 2012-08-27.
  2. ↑ 2.0 2.1 Rawls, Scott M.; Teresa Gomez; Zhe Ding; Robert B. Raffa (2007-12-01). "Differential behavioral effect of the TRPM8/TRPA1 channel agonist icilin (AG-3-5)". European Journal of Pharmacology 575 (1–3): 103–104. doi:10.1016/j.ejphar.2007.07.060. PMID 17765220.

See also