TNFAIP1

Tumor necrosis factor, alpha-induced protein 1 (endothelial)
Identifiers
SymbolsTNFAIP1 ; B12; B61; BTBD34; EDP1; hBACURD2
External IDsOMIM: 191161 MGI: 104961 HomoloGene: 22519 GeneCards: TNFAIP1 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez712621927
EnsemblENSG00000109079ENSMUSG00000017615
UniProtQ13829O70479
RefSeq (mRNA)NM_021137NM_001159392
RefSeq (protein)NP_066960NP_001152864
Location (UCSC)Chr 17:
26.66 – 26.67 Mb
Chr 11:
78.52 – 78.54 Mb
PubMed search

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.[1][2][3]

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.[3]

References

  1. Dixit VM, Green S, Sarma V, Holzman LB, Wolf FW, O'Rourke K, Ward PA, Prochownik EV, Marks RM (Mar 1990). "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin". J Biol Chem 265 (5): 2973–8. PMID 2406243.
  2. Holzman LB, Marks RM, Dixit VM (Dec 1990). "A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein". Mol Cell Biol 10 (11): 5830–8. PMC 361366. PMID 2233719.
  3. 3.0 3.1 "Entrez Gene: TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)".

Further reading