TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein is a protein that in humans is encoded by the TGFB1I1 gene.[1][2]
Interactions
TGFB1I1 has been shown to interact with PTPN12,[3] PTK2,[1][4][5] Androgen receptor,[6][7] PTK2B,[1][5][6] Dopamine transporter[8] and Hsp27.[9]
See also
References
- ↑ 1.0 1.1 1.2 Matsuya M, Sasaki H, Aoto H, Mitaka T, Nagura K, Ohba T, Ishino M, Takahashi S, Suzuki R, Sasaki T (February 1998). "Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions". J Biol Chem 273 (2): 1003–14. doi:10.1074/jbc.273.2.1003. PMID 9422762.
- ↑ Fujimoto N, Yeh S, Kang HY, Inui S, Chang HC, Mizokami A, Chang C (April 1999). "Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate". J Biol Chem 274 (12): 8316–21. doi:10.1074/jbc.274.12.8316. PMID 10075738.
- ↑ Nishiya, N; Iwabuchi Y; Shibanuma M; Côté J F; Tremblay M L; Nose K (April 1999). "Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain". J. Biol. Chem. (UNITED STATES) 274 (14): 9847–53. doi:10.1074/jbc.274.14.9847. ISSN 0021-9258. PMID 10092676.
- ↑ Nishiya, N; Tachibana K; Shibanuma M; Mashimo J I; Nose K (August 2001). "Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase". Mol. Cell. Biol. (United States) 21 (16): 5332–45. doi:10.1128/MCB.21.16.5332-5345.2001. ISSN 0270-7306. PMC 87257. PMID 11463817.
- ↑ 5.0 5.1 Thomas, S M; Hagel M; Turner C E (January 1999). "Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin". J. Cell. Sci. (ENGLAND) 112 (2): 181–90. ISSN 0021-9533. PMID 9858471.
- ↑ 6.0 6.1 Wang, Xin; Yang Yue; Guo Xiaojian; Sampson Erik R; Hsu Cheng-Lung; Tsai Meng-Yin; Yeh Shuyuan; Wu Guan; Guo Yinglu; Chang Chawnshang (May 2002). "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator". J. Biol. Chem. (United States) 277 (18): 15426–31. doi:10.1074/jbc.M111218200. ISSN 0021-9258. PMID 11856738.
- ↑ He, Bin; Minges John T; Lee Lori W; Wilson Elizabeth M (March 2002). "The FXXLF motif mediates androgen receptor-specific interactions with coregulators". J. Biol. Chem. (United States) 277 (12): 10226–35. doi:10.1074/jbc.M111975200. ISSN 0021-9258. PMID 11779876.
- ↑ Carneiro, Ana M; Ingram Susan L; Beaulieu Jean-Martin; Sweeney Ava; Amara Susan G; Thomas Sheila M; Caron Marc G; Torres Gonzalo E (August 2002). "The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter". J. Neurosci. (United States) 22 (16): 7045–54. PMID 12177201.
- ↑ Jia, Y; Ransom R F; Shibanuma M; Liu C; Welsh M J; Smoyer W E (October 2001). "Identification and characterization of hic-5/ARA55 as an hsp27 binding protein". J. Biol. Chem. (United States) 276 (43): 39911–8. doi:10.1074/jbc.M103510200. ISSN 0021-9258. PMID 11546764.
External links
- TGFB1I1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- NURSA C148
Further reading
- Yeh S, Sampson ER, Lee DK et al. (2001). "Functional analysis of androgen receptor N-terminal and ligand binding domain interacting coregulators in prostate cancer.". J. Formos. Med. Assoc. 99 (12): 885–94. PMID 11155740.
- Heitzer MD, DeFranco DB (2007). "Hic-5/ARA55: a prostate stroma-specific AR coactivator.". Steroids 72 (2): 218–20. doi:10.1016/j.steroids.2006.11.010. PMID 17166536.
- Wilson SE, Lloyd SA (1991). "Epidermal growth factor and its receptor, basic fibroblast growth factor, transforming growth factor beta-1, and interleukin-1 alpha messenger RNA production in human corneal endothelial cells.". Invest. Ophthalmol. Vis. Sci. 32 (10): 2747–56. PMID 1716619.
- Shibanuma M, Mashimo J, Kuroki T, Nose K (1994). "Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence.". J. Biol. Chem. 269 (43): 26767–74. PMID 7929412.
- Shibanuma M, Mochizuki E, Maniwa R et al. (1997). "Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblasts.". Mol. Cell. Biol. 17 (3): 1224–35. PMC 231847. PMID 9032249.
- Fujita H, Kamiguchi K, Cho D et al. (1998). "Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase.". J. Biol. Chem. 273 (41): 26516–21. doi:10.1074/jbc.273.41.26516. PMID 9756887.
- Thomas SM, Hagel M, Turner CE (1999). "Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin.". J. Cell. Sci. 112 (2): 181–90. PMID 9858471.
- Nishiya N, Iwabuchi Y, Shibanuma M et al. (1999). "Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain.". J. Biol. Chem. 274 (14): 9847–53. doi:10.1074/jbc.274.14.9847. PMID 10092676.
- Turner CE, Brown MC, Perrotta JA et al. (1999). "Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.". J. Cell Biol. 145 (4): 851–63. doi:10.1083/jcb.145.4.851. PMC 2133183. PMID 10330411.
- Liu S, Thomas SM, Woodside DG et al. (2000). "Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.". Nature 402 (6762): 676–81. doi:10.1038/45264. PMID 10604475.
- Yang L, Guerrero J, Hong H et al. (2000). "Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix.". Mol. Biol. Cell 11 (6): 2007–18. doi:10.1091/mbc.11.6.2007. PMC 14899. PMID 10848625.
- Oda A, Ochs HD, Lasky LA et al. (2001). "CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.". Blood 97 (9): 2633–9. doi:10.1182/blood.V97.9.2633. PMID 11313252.
- Nishiya N, Tachibana K, Shibanuma M et al. (2001). "Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase.". Mol. Cell. Biol. 21 (16): 5332–45. doi:10.1128/MCB.21.16.5332-5345.2001. PMC 87257. PMID 11463817.
- Jia Y, Ransom RF, Shibanuma M et al. (2001). "Identification and characterization of hic-5/ARA55 as an hsp27 binding protein.". J. Biol. Chem. 276 (43): 39911–8. doi:10.1074/jbc.M103510200. PMID 11546764.
- Ting HJ, Yeh S, Nishimura K, Chang C (2002). "Supervillin associates with androgen receptor and modulates its transcriptional activity.". Proc. Natl. Acad. Sci. U.S.A. 99 (2): 661–6. doi:10.1073/pnas.022469899. PMC 117362. PMID 11792840.
- Denhez F, Wilcox-Adelman SA, Baciu PC et al. (2002). "Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5.". J. Biol. Chem. 277 (14): 12270–4. doi:10.1074/jbc.M110291200. PMID 11805099.
- Wang X, Yang Y, Guo X et al. (2002). "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator.". J. Biol. Chem. 277 (18): 15426–31. doi:10.1074/jbc.M111218200. PMID 11856738.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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