TEKT1
Tektin 1 | |||||||||||
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Identifiers | |||||||||||
Symbol | TEKT1 | ||||||||||
External IDs | OMIM: 609002 MGI: 1333819 HomoloGene: 7973 GeneCards: TEKT1 Gene | ||||||||||
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Orthologs | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | 83659 | 21689 | |||||||||
Ensembl | ENSG00000167858 | ENSMUSG00000020799 | |||||||||
UniProt | Q969V4 | Q9DAJ2 | |||||||||
RefSeq (mRNA) | NM_053285 | NM_011569 | |||||||||
RefSeq (protein) | NP_444515 | NP_035699 | |||||||||
Location (UCSC) | Chr 17: 6.69 – 6.74 Mb | Chr 11: 72.34 – 72.36 Mb | |||||||||
PubMed search | |||||||||||
Tektin 1 is a protein that in humans is encoded by the TEKT1 gene.[1][2]
Function
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.[1]
References
- ↑ 1.0 1.1 "Entrez Gene: tektin 1".
- ↑ Xu M, Zhou Z, Cheng C, Zhao W, Tang R, Huang Y, Wang W, Xu J, Zeng L, Xie Y, Mao Y (December 2001). "Cloning and characterization of a novel human TEKTIN1 gene". Int. J. Biochem. Cell Biol. 33 (12): 1172–82. doi:10.1016/S1357-2725(01)00089-9. PMID 11606253.
Further reading
- Strausberg RL, Feingold EA, Grouse LH et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Rose JE, Behm FM, Drgon T et al. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.". Mol. Med. 16 (7-8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Newby PR, Pickles OJ, Mazumdar S et al. (2010). "Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.". Eur. J. Hum. Genet. 18 (9): 1021–6. doi:10.1038/ejhg.2010.55. PMC 2987410. PMID 20442750.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Iguchi N, Tanaka H, Nakamura Y et al. (2002). "Cloning and characterization of the human tektin-t gene.". Mol. Hum. Reprod. 8 (6): 525–30. doi:10.1093/molehr/8.6.525. PMID 12029069.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.