TDRKH

Tudor and KH domain containing

PDB rendering based on 1we8.

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
2DIQ, 3FDR

Identifiers

TDRKH ; TDRD2

External IDs

OMIM: 609501 MGI: 1919884 HomoloGene: 4999 GeneCards: TDRKH Gene

Gene ontology
Molecular function	• RNA binding
Cellular component	• mitochondrion • pi-body • piP-body
Biological process	• male meiosis • spermatogenesis • fertilization • cell differentiation • gene silencing by RNA • piRNA metabolic process • DNA methylation involved in gamete generation
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000182134

ENSMUSG00000041912

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 1:
151.74 – 151.76 Mb

Chr 3:
94.41 – 94.43 Mb

PubMed search

Tudor and KH domain-containing protein is a protein that in humans is encoded by the TDRKH gene.^[1]^[2]

References

↑ Lamb FS, Barna TJ, Goud C, Marenholz I, Mischke D, Schutte BC (May 2000). "Complex RNA processing of TDRKH, a novel gene encoding the putative RNA-binding tudor and KH domains". Gene 246 (1-2): 209–18. doi:10.1016/S0378-1119(00)00087-1. PMID 10767542.
↑ "Entrez Gene: TDRKH tudor and KH domain containing".

Further reading

Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Côté J, Richard S (2005). "Tudor domains bind symmetrical dimethylated arginines.". J. Biol. Chem. 280 (31): 28476–83. doi:10.1074/jbc.M414328200. PMID 15955813.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

PDB gallery

1we8: Solution structure of KH domain in protein BAB28342

2diq: Solution structure of the TUDOR domain of Tudor and KH domain containing protein