TAX1BP1

Tax1 (human T-cell leukemia virus type I) binding protein 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsTAX1BP1 ; CALCOCO3; T6BP; TXBP151
External IDsOMIM: 605326 MGI: 1289308 HomoloGene: 4395 GeneCards: TAX1BP1 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez888752440
EnsemblENSG00000106052ENSMUSG00000004535
UniProtQ86VP1Q3UKC1
RefSeq (mRNA)NM_001079864NM_025816
RefSeq (protein)NP_001073333NP_080092
Location (UCSC)Chr 7:
27.78 – 27.88 Mb
Chr 6:
52.71 – 52.77 Mb
PubMed search

Tax1-binding protein 1 is a protein that in humans is encoded by the TAX1BP1 gene.[1]

Interactions

TAX1BP1 has been shown to interact with TNFAIP3[2] and TRAF6.[3] TAX1BP1 binds to TNFAIP3 or TRAF6 and suppresses NF-kappaB transcriptional activation.

References

  1. "Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1".
  2. De Valck, D; Jin D Y; Heyninck K; Van de Craen M; Contreras R; Fiers W; Jeang K T; Beyaert R (July 1999). "The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases". Oncogene (ENGLAND) 18 (29): 4182–90. doi:10.1038/sj.onc.1202787. ISSN 0950-9232. PMID 10435631.
  3. Ling, L; Goeddel D V (August 2000). "T6BP, a TRAF6-interacting protein involved in IL-1 signaling". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 97 (17): 9567–72. doi:10.1073/pnas.170279097. ISSN 0027-8424. PMC 16905. PMID 10920205.

Further reading