Syntaxin binding protein 3

Syntaxin binding protein 3

PDB rendering based on 2pjx.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsSTXBP3 ; MUNC18-3; MUNC18C; PSP; UNC-18C
External IDsOMIM: 608339 MGI: 107362 HomoloGene: 5260 GeneCards: STXBP3 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez681420912
EnsemblENSG00000116266ENSMUSG00000027882
UniProtO00186Q60770
RefSeq (mRNA)NM_007269NM_011504
RefSeq (protein)NP_009200NP_035634
Location (UCSC)Chr 1:
109.29 – 109.35 Mb
Chr 3:
108.79 – 108.84 Mb
PubMed search

Syntaxin-binding protein 3 is a protein that in humans is encoded by the STXBP3 gene.[1][2]

Interactions

Syntaxin binding protein 3 has been shown to interact with STX2[3] and STX4.[3][4]

References

  1. Reed GL, Houng AK, Fitzgerald ML (May 1999). "Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion". Blood 93 (8): 2617–26. PMID 10194441.
  2. "Entrez Gene: STXBP3 syntaxin binding protein 3".
  3. 3.0 3.1 Schraw, Todd D; Lemons Paula P; Dean William L; Whiteheart Sidney W (Aug 2003). "A role for Sec1/Munc18 proteins in platelet exocytosis". Biochem. J. (England) 374 (Pt 1): 207–17. doi:10.1042/BJ20030610. ISSN 0264-6021. PMC 1223584. PMID 12773094.
  4. Widberg, Charlotte H; Bryant Nia J; Girotti Milena; Rea Shane; James David E (Sep 2003). "Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation". J. Biol. Chem. (United States) 278 (37): 35093–101. doi:10.1074/jbc.M304261200. ISSN 0021-9258. PMID 12832401.

Further reading