Streptomyces coelicolor
| Streptomyces coelicolor | |
|---|---|
| Scientific classification | |
| Domain: | Bacteria |
| Phylum: | Actinobacteria |
| Order: | Actinomycetales |
| Family: | Streptomycetaceae |
| Genus: | Streptomyces |
| Species: | S. coelicolor |
| Binomial name | |
| Streptomyces coelicolor | |
Streptomyces coelicolor is a soil-dwelling Gram-positive bacterium that belongs to the genus Streptomyces.[1]
Genome
The genome of one strain of S. coelicolor was sequenced in 2002.[2] It contains 8,667,507 bp, encoding 7,825 predicted genes, including over 20 gene clusters for the synthesis of known or predicted natural products.
Usage in biotechnology
Strains of S. coelicolor produce various antibiotics, including actinorhodin, methylenomycin, undecylprodigiosin,[3] and perimycin.[4][5] Certain strains of S. coelicolor can be used for heterologous protein expression.[1]
References
- ↑ 1.0 1.1 "Streptomyces coelicolor". John Innes Center. Retrieved 25 January 2010.
- ↑ Bentley SD, Chater KF, Cerdeño-Tárraga AM, et al. (May 2002). "Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)". Nature 417 (6885): 141–7. doi:10.1038/417141a. PMID 12000953.
- ↑ Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. PMC 178074. PMID 8655502.
- ↑ Liu CM, McDaniel LE, Schaffner CP (March 1972). "Fungimycin, biogenesis of its aromatic moiety". The Journal of Antibiotics 25 (3): 187–8. doi:10.7164/antibiotics.25.187. PMID 5034814.
- ↑ Lee CH, Schaffner CP (May 1969). "Perimycin. The structure of some degradation products". Tetrahedron 25 (10): 2229–32. doi:10.1016/S0040-4020(01)82770-8. PMID 5788396.
Further reading
- Galet, Justine; Deveau, Aurélie; Hôtel, Laurence; Leblond, Pierre; Frey‐Klett, Pascale; Aigle, Bertrand (September 2014). "Gluconic acid‐producing Pseudomonas sp. prevent γ‐actinorhodin biosynthesis by Streptomyces coelicolor A3(2)". Archives of Microbiology 196 (9): 619–627. doi:10.1007/s00203-014-1000-4.