Spermine synthase

Spermine synthase
Identifiers
EC number 2.5.1.22
CAS number 74812-43-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Spermine synthase (EC 2.5.1.22, spermidine aminopropyltransferase, spermine synthetase) is an enzyme that converts spermidine into spermine.[1][2] This enzyme catalyses the following chemical reaction

S-adenosylmethioninamine + spermidine \rightleftharpoons S-methyl-5'-thioadenosine + spermine

References

  1. ↑ Hibasami, H., Borchardt, R.T., Chen, S.-Y., Coward, J.K. and Pegg, A.E. (1980). "Studies of inhibition of rat spermidine synthase and spermine synthase". Biochem. J. 187 (2): 419–428. PMC 1161808. PMID 7396856.
  2. ↑ Pajula, R.-L., Raina, A. and Eloranta, T. (1979). "Polyamine synthesis in mammalian tissues. Isolation and characterization of spermine synthase from bovine brain". Eur. J. Biochem. 101 (2): 619–626. doi:10.1111/j.1432-1033.1979.tb19756.x. PMID 520313.

External links