Spafford
Spafford may refer to::
- Belle S. Spafford (1895–1982), former president of the Relief Society
- Gene Spafford (born 1956), professor of computer science at Purdue University
- Horatio Spafford (1828-1888), author of the hymn "It Is Well With My Soul"
- Suzy Spafford (born 1945), cartoonist, creator of "Suzy's Zoo"