Sophoradin

Sophoradin
Chemical structure of sophoradin
Names
IUPAC name
(E)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Other names
2', 4, 4'-trihydroxy-3, 3', 5-tris (3-methyl-2-butenyl) chalcone
Identifiers
23057-54-7
ChemSpider 4479146
Jmol-3D images Image
PubChem 5321393
Properties
C30H36O4
Molar mass 460.60 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Sophoradin is an isoprenyl chalconoid,[1] a type of polyphenolic compound, found in Sophora tonkinensis, a herb used in traditional Chinese medicine.

Sofalcone is an oral gastrointestinal medication and a synthetic derivative of sophoradin.[2]

References

  1. Synthesis of Isoprenyl Chalcone “Sophoradin” Isolated from Sophora subprostrata. Kazuaki Kyogoku, Katsuo Hatayama, Sadakazu Yokamori, Teruya Seki and Ichiro Tanaka, Agricultural and Biological Chemistry, Vol.39 , No.1(1975) pp.133-138
  2. Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R (August 1987). "Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin". Hepatogastroenterology 34 (4): 164–70. PMID 3478294.