Soo Line

Soo Line may refer to:

• Minneapolis, St. Paul and Sault Ste. Marie Railroad, major railroad west of Minneapolis-St. Paul; merged into the Soo Line Railroad (see below) in 1961
• Soo Line Building, U.S. highrise in Minneapolis, Minnesota
• Soo Line Corporation, corporation that manages the Soo Line Railroad
• Soo Line Depot (disambiguation), various places
• Soo Line locomotives, a list page
• Soo Line Railroad, Canadian Pacific Railway subsidiary