Small nucleolar RNA snoZ7/snoR77

Small nucleolar RNA snoZ7/snoR77
Predicted secondary structure and sequence conservation of snoZ7
Identifiers
Symbol snoZ7
Alt. Symbols snoR77
Rfam RF00268
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000593

The snoRNA snoZ7/snoZ77 family contains related non-coding RNA molecules that are members of the C/D class of snoRNA which contain the C box motif (UGAUGA) and the D box motif (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1][2] snoZ7 RNA guides the methylation of 25S rRNA position A1372, whereas SnoR77Y guides the methylation of 18S rRNA at position U580. This family of snoRNAs has been found in plant species such as Arabidopsis thaliana.

References

  1. ↑ Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC 134041. PMID 12215523.
  2. ↑ Marker, C.; Zemann, A.; Terhörst, T.; Kiefmann, M.; Kastenmayer, J. P.; Green, P.; Bachellerie, J. P.; Brosius, J. R.; Hüttenhofer, A. (10 December 2002). "Experimental RNomics: identification of 140 candidates for small non-messenger RNAs in the plant Arabidopsis thaliana". Current Biology 12 (23): 2002–2013. doi:10.1016/S0960-9822(02)01304-0. PMID 12477388.

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