Small nucleolar RNA snR57

Small nucleolar RNA snR57
Predicted secondary structure and sequence conservation of snosnR57
Identifiers
Symbol	snosnR57
Rfam	RF00474
Other data
RNA type	Gene; snRNA; snoRNA; CD-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0000593

snoRNA snR57 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR57 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.^[1] snoRNA snR57 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.^[2]

References

External links

• Page for Small nucleolar RNA snR57 at Rfam
• Link to snR57 at the FournierLab/snoRNAdb.