Small nucleolar RNA SNORD27

Small nucleolar RNA SNORD27
Predicted secondary structure and sequence conservation of SNORD27
Identifiers
Symbol SNORD27
Alt. Symbols U27
Rfam RF00086
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000593

Small nucleolar RNA SNORD27 (also known as U27 in mammals and snR74 in fungi) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U27 is encoded within the U22 snoRNA host gene (UHG) in mammals[1] and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.[2] This family also contains several related snoRNAs from yeast and plants.

References

  1. Tycowski, KT; Shu MD; Steitz JA (1996). "A mammalian gene with introns instead of exons generating stable RNA products". Nature 379 (6564): 464466. doi:10.1038/379464a0. PMID 8559254.
  2. Tycowski, KT; Smith CM; Shu MD; Steitz JA (1996). "A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus". Proc Natl Acad Sci USA 93 (25): 1448014485. doi:10.1073/pnas.93.25.14480. PMC 26158. PMID 8962077.

External links