Small nucleolar RNA SNORA71

Small nucleolar RNA SNORA71
Predicted secondary structure and sequence conservation of SNORA71
Identifiers
Symbol SNORA71
Alt. Symbols U71
Rfam RF00056
Other data
RNA type Gene; snRNA; snoRNA; H/ACA-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000594

In molecular biology, U71 belongs to the H/ACA class of Small nucleolar RNA (snoRNAs). snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs.[1] Targets may include ribosomal and spliceosomal RNAs but the exact function of many snoRNAs, including U71, is unclear.

References

  1. ↑ Kiss, Tamás (2002). "Small Nucleolar RNAs". Cell 109 (2): 145–148. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400.

Further reading

  • Ganot, Philippe; Caizergues-Ferrer, Michèle; Kiss, Tamás (1 April 1997). "The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation". Genes & Development 11 (7): 941–956. doi:10.1101/gad.11.7.941. PMID 9106664.
  • Bachellerie, Jean-Pierre; Cavaillé, Jérôme; Hüttenhofer, Alexander (August 2002). "The expanding snoRNA world". Biochimie 84 (8): 775–790. doi:10.1016/S0300-9084(02)01402-5. PMID 12457565.

External links