Small nucleolar RNA SNORA62

Small nucleolar RNA SNORA62/SNORA6 family
Predicted secondary structure and sequence conservation of SNORA62
Identifiers
Symbol SNORA62
Alt. Symbols E2
Rfam RF00091
Other data
RNA type Gene; snRNA; snoRNA; H/ACA-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000594

Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs.[1]

E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA.[2] E2 is encoded in introns in the gene for a laminin-binding protein.[3]

This family also contains the related ACA6, M2 and MBI-136 snoRNAs.[2][4]

References

  1. Huttenhofer, Alexander; Kiefmann, Martin; Meier-Ewert, Sebastian; O'Brien, John; Lehrach, Hans; Bachellerie, Jean-Pierre; Brosius, Jürgen (1 June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal 20 (11): 2943–2953. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.
  2. 2.0 2.1 Mishra, RK; Eliceiri GL (1997). "Three small nucleolar RNAs that are involved in ribosomal RNA precursor processing". Proc Natl Acad Sci USA 94 (10): 49724977. doi:10.1073/pnas.94.10.4972. PMC 24615. PMID 9144174.
  3. Selvamurugan, N; Eliceiri GL (1995). "The gene for human E2 small nucleolar RNA resides in an intron of a laminin-binding protein gene". Genomics 30 (2): 400401. PMID 8586453.
  4. Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.

External links