Small nucleolar RNA MBI-161

Small nucleolar RNA SNORA31
Predicted secondary structure and sequence conservation of SNORA31
Identifiers
Symbol SNORA31
Alt. Symbols snoMBI-161
Rfam RF00322
Other data
RNA type Gene; snRNA; snoRNA; H/ACA-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000594

Small nucleolar RNA MBI-161 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".[1]

snoRNA MBI-161 was originally cloned from mouse brain tissues[2] and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs.

References

  1. ↑ Kiss, Tamás (2002). "Small Nucleolar RNAs". Cell 109 (2): 145–148. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400.
  2. ↑ Huttenhofer, Alexander; Kiefmann, Martin; Meier-Ewert, Sebastian; O'Brien, John; Lehrach, Hans; Bachellerie, Jean-Pierre; Brosius, Jürgen (1 June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal 20 (11): 2943–2953. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.

External links