Sesamin

Sesamin
Names
IUPAC name
5,5'-(1S,3aR,4S,6aR)-tetrahydro-1H,3H- furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole)
Other names
Fagarol
Sezamin
pseudocubebin
Episesamin
Asarinin
D-(+)-Sesamin
d-Sesamin
(+)-Sesamin
l-sesamin
Identifiers
607-80-7 Yes
ChEBI CHEBI:66470 
ChEMBL ChEMBL252915 
ChemSpider 65258 
Jmol-3D images Image
KEGG C10882 
PubChem 5204
Properties
C20H18O6
Molar mass 354.35 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Sesamin is a lignan isolated from the bark of Fagara plants and from sesame oil. It has been used as a dietary fat-reduction supplement, although no controlled studies on this application have been performed.[1] Its major metabolite is enterolactone, which has an elimination half life of less than 6 hours.[2] Sesamin and sesamolin are minor components of sesame oil,[3] on average comprising only 0.14% of the oil by mass.[4]

See also

References

  1. ↑ Kamal-Eldin A, Moazzami A, Washi S (January 2011). "Sesame seed lignans: potent physiological modulators and possible ingredients in functional foods & nutraceuticals". Recent Pat Food Nutr Agric 3 (1): 17–29. doi:10.2174/2212798411103010017. PMID 21114470.
  2. ↑ Peñalvo JL, Heinonen SM, Aura AM, Adlercreutz H (May 2005). "Dietary sesamin is converted to enterolactone in humans". J. Nutr. 135 (5): 1056–1062. PMID 15867281.
  3. ↑ Lim JS, Adachi Y, Takahashi Y and Ide T (Jan 2007). "Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats.". Br J Nutr 97 (1): 85–95. doi:10.1017/S0007114507252699. PMID 17217563.
  4. ↑ Ikan, Raphael (1991). Natural Products: A Laboratory Guide 2nd Ed. San Diego: Academic Press, Inc. p. 50. ISBN 0123705517.

External links