Sean Curran (scientist)
Sean Curran is an assistant professor in Gerontology at the USC Davis School of Gerontology with joint appointments in Molecular and Computational Biology (USC Dana and David Dornsife College of Letters, Arts and Sciences) and Biochemistry and Molecular Biology (Keck School of Medicine of USC). He studies molecular genetics of exceptional longevity.[1]
Research
Curran and his co-author Gary Ruvkun discovered approximately 60 highly-conserved genes that are essential for development but can significantly increase lifespan when inactivated in adulthood.[2][3]
Biography
He earned his B.S. from UCLA in 1999, his Ph.D. from UCLA in 2004 and completed postdoctoral training at Harvard Medical School and Massachusetts General Hospital from 2004-2010.[4]
Selected publications
- Pang S, Curran SP. Adaptive capacity to bacterial diet modulates aging in C. elegans. Cell Metab. 2014 Feb 4;19(2):221-31. doi: 10.1016/j.cmet.2013.12.005. Epub 2014 Jan 16.
- Curran SP, Wu X, Riedel C and Ruvkun G. A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Nature. 2009 Jun 25;459(7250):1079-84
- Curran SP and Ruvkun G (2007) Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet Apr 6;3(4):e56.
References
- ↑ "Sean Curran Faculty Profile". USC Davis School of Gerontology. Retrieved 20 March 2012.
- ↑ Wade, Nicholas (9 June 2009). "In Worms, Genetic Clues to Extending Longevity". The New York Times. Retrieved 20 March 2012.
- ↑ Keim, Brandon (8 June 2009). "The Secret to Roundworm Longevity: Sex Cells". Wired. Retrieved 21 March 2012.
- ↑ "CCIB: Ruvkun Lab". Retrieved 20 March 2012.