Salvinorin
Salvinorins are a group of natural chemical compounds and their structural analogs. Several salvinorins have been isolated from Salvia divinorum. They are classified as diterpenoid furanolactones. Salvinorin A is a hallucinogen with dissociative effects.
Several salvinorins have been isolated and characterized.
Name | Structure | R1 | R2 | Chemical formula | Molar mass | CAS number | PubChem |
---|---|---|---|---|---|---|---|
Salvinorin A | –OCOCH3 | − | C23H28O8 | 432.46 g·mol−1 | 83729-01-5 | PubChem 128563 | |
Salvinorin B | –OH | − | C21H26O7 | 390.43 g·mol−1 | 92545-30-7 | PubChem 11440685 | |
Salvinorin C | –OCOCH3 | –OCOCH3 | C25H30O9 | 475.29 g·mol−1 | 385785-99-9 | – | |
Salvinorin D | –OCOCH3 | –OH | C23H28O8 | 432.47 g·mol−1 | 540770-13-6 | – | |
Salvinorin E | –OH | –OCOCH3 | C23H28O8 | 432.47 g·mol−1 | 540770-14-7 | – | |
Salvinorin F | –OH | –H | C21H26O6 | 374.43 g·mol−1 | 540770-15-8 | – | |
Salvinorin G | =O | –OCOCH3 | C23H26O8 | 430.45 g·mol−1 | 866622-54-0 | – | |
Salvinorin H | –OH | –OH | C21H26O7 | 390.43 g·mol−1 | 872004-62-1 | – | |
Salvinorin I | – | – | C21H28O7 | 392.45 g·mol−1 | 917951-71-4 | – | |
17α-Salvinorin J | – | – | C23H30O8 | 434.49 g·mol−1 | 1157894-83-1 | – | |
17β-Salvinorin J | – | – | C23H30O8 | 434.49 g·mol−1 | 1157894-85-3 | – |
Analogs
Because of their biological activities, synthetic and semi-synthetic analogs have been prepared for study. Semi-synthetic analogs include salvinorin B ethoxymethyl ether and salvinorin B methoxymethyl ether. Fully synthetic analogs include herkinorin.